The human cytomegalovirus major immediate-early gene

被引:81
作者
Stenberg, RM
机构
[1] Department of Microbiology and Immunology, Eastern Virginia Medical School, Norfolk, VA
关键词
IE1; IE2; activation; repression; IE72; IE86;
D O I
10.1159/000150505
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Immediate-early genes function to regulate viral and cellular gene expression during the course of virus replication. The major immediate-early gene region of human cytomegalovirus plays a key role in affecting activation and repression of viral and cellular genes. These proteins intimately associate and/or interact with viral and cellular proteins during this process. Herein, we will discuss the current understanding of this complex gene region.
引用
收藏
页码:343 / 349
页数:7
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