Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression

被引：51

作者：

Mechoulam, R ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Fac Med, IL-91120 Jerusalem, Israel

来源：

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS | 2002年 / 66卷 / 2-3期

关键词：

D O I：

10.1054/plef.2001.0340

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A short history of the discovery of the main plant cannabinoid, Delta9-tetrahydrocannabinol and of the endogenous cannabinoids anandamide, 2-arachidonoyl glycerol and 2-arachidonyl glyceryl ether (noladin ether) is presented. The role of the cannabinoids in neuroprotection, with emphasis on the endocannabinoids, is described. The unexpected production of aggression by Cannabis and cannabinoids under stressful conditions, published mainly in the past, is summarized. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：93 / 99

页数：7

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