cDNA cloning of human muskelin and localisation of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6 B1/B2 by physical mapping and FISH

被引：8

作者：

Adams, JC

Zhang, L

机构：

[1] UCL, MRC, Mol Cell Biol Lab, London WC1E 6BT, England

[2] UCL, MRC, Dept Biochem & Mol Biol, London WC1E 6BT, England

来源：

CYTOGENETICS AND CELL GENETICS | 1999年 / 87卷 / 1-2期

基金：

英国惠康基金;

关键词：

D O I：

10.1159/000015385

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Muskelin is a novel intracellular protein, identified in mouse cells, that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin-1. We report that human muskelin is 98% identical with mouse muskelin at the amino acid level. The human muskelin gene is located at 7q32. The mouse muskelin gene maps syntenically at chromosome 6 B1/B2. Copyright (C) 1999 S. Karger AG, Basel.

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页码：19 / 21

页数：3

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