Regioselective substitution of 2,3-dichloro-6-amino-quinoxaline

被引：11

作者：

Ford, E ^{[1
]}

Brewster, A ^{[1
]}

Jones, G ^{[1
]}

Bailey, J ^{[1
]}

Sumner, N ^{[1
]}

机构：

[1] AstraZeneca, Macclesfield SK10 4TG, Cheshire, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 17期

关键词：

regiochemistry; quinoxalines;

D O I：

10.1016/S0040-4039(00)00349-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The novel regioselective substitution of 2,3-dichloro-6-amino-quinoxaline is described. A range of nucleophiles were used to provide 2,3-disubstituted-6-aminoquinoxalines with complementary regiochemistry to that obtainable using published methodology. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3197 / 3198

页数：2

共 4 条

[1]

ABDELMEGEID FME, 1980, EGYPT J CHEM, V20, P427

[2] ISOLATION OF THE INTERMEDIATES AND IMPROVED SYNTHESIS OF PYRIDO[1',2'/1,2]IMIDAZOL[4,5-B]PYRAZINES AND PYRIDO[1',2'/1,2]IMIDAZOL]4,5-B]QUINOXALINES [J].