Management of cow's milk protein allergy in infants and young children: An expert panel perspective

被引：57

作者：

Allen, Katrina J. ^{[1
,2
,4
]}

Davidson, Geoffrey P. ^{[3
]}

Day, Andrew S. ^{[5
]}

Hill, David J. ^{[2
]}

Kemp, Andrew S. ^{[6
]}

Peake, Jane E. ^{[7
]}

Prescott, Susan L. ^{[8
]}

Shugg, Albert ^{[9
]}

Sinn, John K. H. ^{[10
]}

Heine, Ralf G. ^{[1
,2
,4
]}

机构：

[1] Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[2] Royal Childrens Hosp, Dept Allergy & Immunol, Melbourne, Vic, Australia

[3] Womens & Childrens Hosp, Dept Gastroenterol, Adelaide, SA, Australia

[4] Univ Melbourne, Dept Paediat, Melbourne, Vic, Australia

[5] Sydney Childrens Hosp, Dept Gastroenterol, Randwick, NSW, Australia

[6] Childrens Hosp Westmead, Dept Allergy Immunol & Infect Dis, Sydney, NSW, Australia

[7] Child Hlth Univ Queensland, Dept Paediat, Brisbane, Qld, Australia

[8] Univ Western Australia, Princess Margaret Hosp, Sch Paediat & Child Hlth, Nedlands, WA 6009, Australia

[9] Univ Tasmania, Rural Clin Sch, Burnie, Tas 7320, Australia

[10] Royal N Shore Hosp, Dept Neonatol, Sydney, NSW, Australia

来源：

JOURNAL OF PAEDIATRICS AND CHILD HEALTH | 2009年 / 45卷 / 09期

关键词：

anaphylaxis; eosinophilic oesophagitis; food challenge; gastrointestinal; hypoallergenic formula; skin prick test; BREAST-FED INFANTS; FOOD ALLERGY; EOSINOPHILIC ESOPHAGITIS; GASTROESOPHAGEAL-REFLUX; CHRONIC CONSTIPATION; ELIMINATION DIET; DOUBLE-BLIND; FORMULAS; ANAPHYLAXIS; HYDROLYSATE;

D O I：

10.1111/j.1440-1754.2009.01546.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Cow's milk protein allergy is a condition commonly managed by general practitioners and paediatricians. The diagnosis is usually made in the first 12 months of life. Management of immediate allergic reactions and anaphylaxis includes the prevention of accidental food ingestion and provision of an adrenaline autoinjector, if appropriate. By contrast, the clinical course of delayed food-allergic manifestations is characterised by chronicity, and is often associated with nutritional or behavioural sequelae. Correct diagnosis of these non-IgE-mediated conditions may be delayed due to a lack of reliable diagnostic markers. This review aims to guide clinicians in the: (i) diagnostic evaluation (skin prick testing or measurement of food-specific serum IgE levels; indications for diagnostic challenges for suspected IgE- and non-IgE-mediated food allergy), (ii) dietary treatment, (iii) assessment of response to treatment, (iv) differential diagnosis and further diagnostic work-up in non-responders, (v) follow-up assessment of tolerance development and (vi) recommendations for further referral.

引用

页码：481 / 486

页数：6

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