Salen-Ti(OR)(4) complex catalysed trimethylsilylcyanation of aldehydes

被引：90

作者：

Jiang, YZ

Gong, LZ

Feng, XM

Hu, WH

Pan, WD

Li, Z

Mi, AQ

机构：

[1] Union Lab. of Asymmetric Synthesis, Chengdu Inst. of Organic Chemistry, Chinese Academy of Sciences, Chengdu

来源：

TETRAHEDRON | 1997年 / 53卷 / 42期

关键词：

D O I：

10.1016/S0040-4020(97)00984-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral salen-titanium complexes were found to be efficient catalysts fbr the enantioselective trimethylsilylcyanation of aldehydes. An enantioselectivity up to 87.1% e.e. was obtained by using 10mol% Ti(IV)-salen 2d as catalyst. The reaction mechanism was proposed and proved experimentally. (C) 1997 Published by Elsevier Science Ltd.

引用

页码：14327 / 14338

页数：12

共 49 条

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