Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

被引：18

作者：

Djurovic, Srdjan ^{[1
,2
,3
]}

Le Hellard, Stephanie ^{[4
,5
]}

Kahler, Anna K. ^{[1
,2
]}

Jonsson, Erik G. ^{[6
]}

Agartz, Ingrid ^{[1
,6
,7
]}

Steen, Vidar M. ^{[4
,5
]}

Hall, Hakan ^{[6
]}

Wang, August G. ^{[8
]}

Rasmussen, Henrik B. ^{[9
]}

Melle, Ingrid ^{[1
,3
]}

Werge, Thomas ^{[8
]}

Andreassen, Ole A. ^{[1
,3
]}

机构：

[1] Univ Oslo, Dept Psychiat, N-0316 Oslo, Norway

[2] Ullevaal Univ Hosp, Dept Med Genet, Oslo, Norway

[3] Ullevaal Univ Hosp, Div Psychiat, Dept Res & Dev, Oslo, Norway

[4] Haukeland Hosp, Ctr Med Genet & Mol Med, Dr E Martens Res Grp Biol Psychiat, N-5021 Bergen, Norway

[5] Univ Bergen, Dept Clin Med, Bergen Mental Hlth Res Ctr, N-5020 Bergen, Norway

[6] Karolinska Hosp & Inst, HUBIN Project, Dept Clin Neurosci, Stockholm, Sweden

[7] Diakonhjemmet Hosp, Dept Psychiat Res, Oslo, Norway

[8] Copenhagen Univ Hosp, Mental Hlth Ctr Amager, Copenhagen, Denmark

[9] Univ Copenhagen, HS Sct Hans Hosp, Res Inst Biol Psychiat, DK-1168 Copenhagen, Denmark

来源：

PSYCHIATRY RESEARCH | 2009年 / 168卷 / 03期

基金：

瑞典研究理事会; 英国医学研究理事会;

关键词：

TagSNP; 15q26; Candidate gene; REGIONS;

D O I：

10.1016/j.psychres.2008.08.007

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：256 / 258

页数：3

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