A common progenitor at the heart of development

被引：116

作者：

Garry, Daniel J.

Olson, Eric N. ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA

[2] Univ Texas, SW Med Ctr, Dept Mol Biol, Dallas, TX 75390 USA

[3] Univ Texas, SW Med Ctr, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX 75390 USA

来源：

CELL | 2006年 / 127卷 / 06期

关键词：

D O I：

10.1016/j.cell.2006.11.031

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Formation of the heart requires the coordinated functions of cardiac myocytes, smooth muscle cells, endothelial cells, and connective tissue elements. Several recent studies now reveal that these different cell types arise from a common progenitor (Kattman et al., 2006; Moretti et al., 2006; Wu et al., 2006). These findings raise interesting questions about the lineage relationships of cardiovascular progenitor cell populations and suggest possibilities for cardiac repair in both congenital and acquired heart disease.

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收藏

页码：1101 / 1104

页数：4

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