FDG PET: advantages for staging the mediastinum?

被引:10
作者
Franzius, C [1 ]
机构
[1] Univ Hosp Munster, Dept Nucl Med, D-48149 Munster, Germany
关键词
FDG; PET; imaging; staging; mediastinum; lung cancer;
D O I
10.1016/j.lungcan.2004.07.990
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Correctly staging lung cancer is extremely important because treatment options and prognosis differ significantly by stage. In this review, the performance characteristics of positron emission tomography using F-18-fluoro-deoxyglucose (FDG PET) for staging the mediastinum are given in comparison with other non-invasive imaging modalities on the basis of current literature data. There are three meta-anatyses demonstrating that FDG PET is more accurate than CT for detecting mediastinal metastases. First publications suggest that dual-modality PET-CT may provide a further gain in accuracy. Additionally, whole-body FDG PET provides information on M-staging and prognosis. Data comparing FDG PET with other functional imaging modalities or endoscopic ultrasound are limited. The necessity of a histological confirmation of PET results is still under discussion. (C) 2004 Elsevier Science Ltd.
引用
收藏
页码:S69 / S74
页数:6
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