Synthesis and pharmacological activity of philanthotoxin-343 analogs: Antagonists of ionotropic glutamate receptors

被引：18

作者：

Huang, DW

Jiang, H

Nakanishi, K

Usherwood, PNR

机构：

[1] COLUMBIA UNIV,DEPT CHEM,NEW YORK,NY 10027

[2] UNIV NOTTINGHAM,DEPT LIFE SCI,NOTTINGHAM NG7 2RD,ENGLAND

来源：

TETRAHEDRON | 1997年 / 53卷 / 37期

关键词：

D O I：

10.1016/S0040-4020(97)00801-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of two classes of Philanthotoxin-343 analogs is described. Quantitative information on the antagonism of quisqualate-sensitive ionotropic glutamate receptors of insect muscle by these compounds is presented. (C) 1997 Elsevier Science Ltd.

引用

页码：12391 / 12404

页数：14

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