Synthesis of N-(2-pyranyl)- and N-cyclohexylindole derivatives via stereoselective addition of indole nucleophiles to organomolybdenum complexes

被引：8

作者：

Bjurling, E

Johansson, MH

Andersson, CM

机构：

[1] ACADIA Pharmaceut AS, Synthet Chem, DK-2600 Glostrup, Denmark

[2] Univ Lund, Ctr Chem, Dept Quim Organ 1, S-22100 Lund, Sweden

[3] Univ Lund, Ctr Chem, Dept Inorgan Chem 1, S-22100 Lund, Sweden

来源：

ORGANOMETALLICS | 1999年 / 18卷 / 26期

关键词：

D O I：

10.1021/om9906060

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Indol-1-yl-substituted dihydropyranyl- and cyclohexenylmolybdenum complexes were obtained via nucleophilic addition of a variety of substituted indoles to cationic (pyran)- and (cyclohexadiene)molybdenum complexes. The efficiency of these addition reactions was found to be highly dependent upon the substitution pattern in the nucleophile. Oxidative decomplexation with iodine smoothly delivered the corresponding allylic iodide in good yield. Complex 6b, was characterized by X-ray crystallography.

引用

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页码：5606 / 5613

页数：8

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