Ebola virus disease: Biological and diagnostic evolution from 2014 to 2017

被引：11

作者：

Merens, A. ^{[1
]}

Bigaillon, C. ^{[1
]}

Delaune, D. ^{[1
]}

机构：

[1] Hop Instruct Armees Begin, Lab Biol, 69 Ave Paris, F-94160 St Mande, France

来源：

MEDECINE ET MALADIES INFECTIEUSES | 2018年 / 48卷 / 02期

关键词：

Biosafety; Diagnosis; Ebola virus; POINT-OF-CARE; ANTIGEN RAPID TEST; BIOTHREAT-E TEST; FIELD VALIDATION; PERSISTENCE; PCR; MANAGEMENT; FILMARRAY; CHEMISTRY; OUTCOMES;

D O I：

10.1016/j.medmal.2017.11.002

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The Ebola virus disease outbreak observed in West Africa from March 2014 to June 2016 has led to many fundamental and applied research works. Knowledge of this virus has substantially increased. Treatment of many patients in epidemic countries and a few imported cases in developed countries led to developing new diagnostic methods and to adapt laboratory organization and biosafety precautions to perform conventional biological analyses. Clinical and biological monitoring of patients infected with Ebola virus disease helped to determine severity criteria and bad prognosis markers. It also contributed to showing the possibility of viral sanctuaries in patients and the risk of transmission after recovery. After a summary of recent knowledge of environmental and clinical viral persistence, we aimed to present new diagnostic methods and other biological tests that led to highlighting the pathophysiological consequences of Ebola virus disease and its prognostic markers. We also aimed to describe our lab experience in the care of Ebola virus-infected patients, especially technical and logistical changes between 2014 and 2017. (C) 2017 Elsevier Masson SAS. All rights reserved.

引用

页码：83 / 94

页数：12

共 47 条

[1] For a reasonable management of viral risk in medical biology [J].

Agut, Henri .

VIROLOGIE, 2015, 19 (04) :165-171

[2]

[Anonymous], 2016, 2014 2016 EB OUTBR W

[3] Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly From Blood [J].

Benzine, Jason W. ;

Brown, Kerry M. ;

Agans, Krystle N. ;

Godiska, Ronald ;

Mire, Chad E. ;

Gowda, Krishne ;

Converse, Brandon ;

Geisbert, Thomas W. ;

Mead, David A. ;

Chander, Yogesh .

JOURNAL OF INFECTIOUS DISEASES, 2016, 214 :S234-S242

[4] Persistence of Ebola Virus in Sterilized Wastewater [J].

Bibby, Kyle ;

Fischer, Robert J. ;

Casson, Leonard W. ;

Stachler, Elyse ;

Haas, Charles N. ;

Munster, Vincent J. .

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2015, 2 (09) :245-249

[5] Field Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection [J].

Boisen, Matthew L. ;

Cross, Robert W. ;

Hartnett, Jessica N. ;

Goba, Augustine ;

Momoh, Mambu ;

Fullah, Mohamed ;

Gbakie, Michael ;

Safa, Sidiki ;

Fonnie, Mbalu ;

Baimba, Francis ;

Koroma, Veronica J. ;

Geisbert, Joan B. ;

McCormick, Stephanie ;

Nelson, Diana K. S. ;

Millett, Molly M. ;

Oottamasathien, Darin ;

Jones, Abby B. ;

Ha Pham ;

Brown, Bethany L. ;

Shaffer, Jeffrey G. ;

Schieffelin, John S. ;

Kargbo, Brima ;

Gbetuwa, Momoh ;

Gevao, Sahr M. ;

Wilson, Russell B. ;

Pitts, Kelly R. ;

Geisbert, Thomas W. ;

Branco, Luis M. ;

Khan, Sheik H. ;

Grant, Donald S. ;

Garry, Robert F. .

JOURNAL OF INFECTIOUS DISEASES, 2016, 214 :S203-S209

[6] ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study [J].

Broadhurst, Mara Jana ;

Kelly, John Daniel ;

Miller, Ann ;

Semper, Amanda ;

Bailey, Daniel ;

Groppelli, Elisabetta ;

Simpson, Andrew ;

Brooks, Tim ;

Hula, Susan ;

Nyoni, Wilfred ;

Sankoh, Alhaji B. ;

Kanu, Santigi ;

Jalloh, Alhaji ;

Ton, Quy ;

Sarchet, Nicholas ;

George, Peter ;

Perkins, Mark D. ;

Wonderly, Betsy ;

Murray, Megan ;

Pollock, Nira R. .

LANCET, 2015, 386 (9996) :867-874

[7] Ebola virus disease diagnosis by real-time RT-PCR: A comparative study of 11 different procedures [J].

Cherpillod, Pascal ;

Schibler, Manuel ;

Vieille, Gael ;

Cordey, Samuel ;

Mamin, Aline ;

Vetter, Pauline ;

Kaiser, Laurent .

JOURNAL OF CLINICAL VIROLOGY, 2016, 77 :9-14

[8] Essentials of filoviral load quantification [J].

Cnops, Lieselotte ;

van Griensven, Johan ;

Honko, Anna N. ;

Bausch, Daniel G. ;

Sprecher, Armand ;

Hill, Charles E. ;

Colebunders, Robert ;

Johnson, Joshua C. ;

Griffiths, Anthony ;

Palacios, Gustavo F. ;

Kraft, Colleen S. ;

Kobinger, Gary ;

Hewlett, Angela ;

Norwood, David A. ;

Sabeti, Pardis ;

Jahrling, Peter B. ;

Formenty, Pierre ;

Kuhn, Jens H. ;

Arien, Kevin K. .

LANCET INFECTIOUS DISEASES, 2016, 16 (07) :E134-E138

[9] Evaluating Environmental Persistence and Disinfection of the Ebola Virus Makona Variant [J].

Cook, Bradley W. M. ;

Cutts, Todd A. ;

Nikiforuk, Aidan M. ;

Poliquin, Philip Guillaume ;

Court, Deborah A. ;

Strong, James E. ;

Theriault, Steven S. .

VIRUSES-BASEL, 2015, 7 (04) :1975-1986

[10] Rhabdomyolysis in Ebola Virus Disease. Results of an Observational Study in a Treatment Center in Guinea [J].

Cournac, Jean Marie ;

Karkowski, Ludovic ;

Bordes, Julien ;

Aletti, Marc ;

Duron, Sandrine ;

Janvier, Frederic ;

Foissaud, Vincent ;

Savini, Helene ;

de Greslan, Thierry ;

Rousseau, Claire ;

Billhot, Magali ;

Gagnon, Nicolas ;

Mac Nab, Christine ;

Dubrous, Philippe ;

Moroge, Sophie ;

Broto, Helene ;

Cotte, Jean ;

Maugey, Nancy ;

Cordier, Pierre-Yves ;

Sagui, Emmanuel ;

Merens, Audrey ;

Rapp, Christophe ;

Quentin, Benoit ;

Granier, Herve ;

Carmoi, Thierry ;

Cellarier, Gilles .

CLINICAL INFECTIOUS DISEASES, 2016, 62 (01) :19-23

← 1 2 3 4 5 →