Got MLL? Definitive hematopoiesis requires MLL gene expression

被引:4
作者
Dorshkind, K [1 ]
Witte, O
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Microbiol Mol Genet & Immunol, Dept Lab Med & Pathol, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Howard Hughes Med Inst, Dept Microbiol Mol Genet & Immunol, Los Angeles, CA 90095 USA
关键词
D O I
10.1016/S1097-2765(04)00159-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A manuscript by Ernst and colleagues in the March 2004 issue of Developmental Cell demonstrates that following hematopoietic stem cell appearance in the AGM, expression of the MLL transcription factor is required for their subsequent differentiation.
引用
收藏
页码:765 / 766
页数:2
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