Immunophilins: Their properties and their potential role in therapeutic drug monitoring

被引：6

作者：

Soldin, SJ

机构：

[1] Childrens Natl Med Ctr, Dept Lab Med, Washington, DC 20010 USA

[2] George Washington Univ, Sch Med, Dept Pathol, Washington, DC USA

[3] George Washington Univ, Sch Med, Dept Pediat, Washington, DC USA

来源：

THERAPEUTIC DRUG MONITORING | 2000年 / 22卷 / 01期

关键词：

immunophilins; sirolimus; tacrolimus; assays;

D O I：

10.1097/00007691-200002000-00009

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

This article reviews recent developments in the immunophilin arena and the current state of knowledge about the biochemical properties of immunophilins. The role of immunophilin-binding assays is also explored with the conclusion that some of these immunosuppressive-drug-binding proteins may provide better assays for sirolimus and tacrolimus than current immunoassays.

引用

页码：44 / 46

页数：3

共 18 条

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BEDNARCZYK B, 1988, CLIN CHEM, V34, P393

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