Biological activity of quercetin-3-O-glucoside, a known plant flavonoid

被引：112

作者：

Razavi, Seyed Mehdi ^{[1
]}

Zahri, Saber ^{[1
]}

Zarrini, Gholamreza ^{[2
]}

Nazemiyeh, Hossein ^{[3
]}

Mohammadi, Sariyeh ^{[1
]}

机构：

[1] Univ Mohaghegh Ardabili, Fac Sci, Dept Biol, Ardebil, Iran

[2] Univ Tabriz, Fac Nat Sci, Dept Anim Sci, Tabriz, Iran

[3] Tabriz Univ Med Sci, Fac Pharm, Dept Pharmacognosy, Tabriz, Iran

来源：

RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2009年 / 35卷 / 03期

关键词：

quercetin; 3-O-glucoside; cytotoxic; phytotoxic; antioxidan; DERIVATIVES; QUERCETIN;

D O I：

10.1134/S1068162009030133

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Cytotoxic, phytotoxic, antimicrobial and antioxidant effects of quercetin 3-O-glucoside (Q3G) isolated by HPLC from aerial parts of Prangos ferulaceae was studied by MTT assay, lettuce germination assay, disk diffusion and DPPH method. Our results showed that Q3G exhibits high antioxidant effect with RC50 of 22 mu g/mL, it has low cytotoxicity and no antibacterial effects. Q3G exhibits high phytotoxic effect with IC50 value of 282.7 mu g/ml, as well. It is assumed that Q3G does not play a defense role in plants and it may act as an allelopatic agent.

引用

页码：376 / 378

页数：3

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