Antigenic variation in the persistence and transmission of the ehrlichia Anaplasma marginale

被引：82

作者：

Palmer, GH ^{[1
]}

Brown, WC ^{[1
]}

Rurangirwa, FR ^{[1
]}

机构：

[1] Washington State Univ, Program Vector Borne Dis, Pullman, WA 99164 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 02期

关键词：

ehrlichia; antigenic variation; persistent infection;

D O I：

10.1016/S1286-4579(00)00271-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tick-borne transmission of ehrlichial pathogens requires rickettsemic reservoir hosts to maintain a population of infected vectors. Persistence in their respective mammalian hosts appears to be a common feature of the tick-transmitted ehrlichiae. How infection persists in immunocompetent hosts is unknown. In this review, we describe studies on Anaplasma marginale, an ehrlichial pathogen of cattle, that support antigenic variation as a primary mechanism of persistence. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：167 / 176

页数：10

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