The structural role of sugars in glycoproteins

被引：126

作者：

Wyss, DF

Wagner, G

机构：

[1] PROCEPT INC, 840 MEM DR, CAMBRIDGE, MA 02139 USA

[2] HARVARD UNIV, SCH MED, DEPT BIOL CHEM & MOL PHARMACOL, BOSTON, MA 02115 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1996年 / 7卷 / 04期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1016/S0958-1669(96)80116-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

To date, high resolution X-ray structures of about 30 glycoproteins have been reported that provide some structural information on glycans. Four solution structures of glycoproteins have been described over the past three years. In all four of these cases, it was shown that glycosylation is stabilizing the glycoprotein structures, indicating that this may be a general glycan function.

引用

收藏

页码：409 / 416

页数：8

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