Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine

被引：45

作者：

Bernal, ML

Sinues, B

Johansson, I

McLellan, RA

Wennerholm, A

Dahl, ML

Ingelman-Sundberg, M

Bertilsson, L ^{[1
]}

机构：

[1] Huddinge Univ Hosp, Karolinska Inst, Dept Med Lab Sci & Technol, Div Clin Pharmacol, SE-14186 Huddinge, Sweden

[2] Univ Zaragoza, Dept Physiol & Pharmacol, Zaragoza, Spain

[3] Karolinska Inst, Inst Environm Med, Div Mol Toxicol, S-10401 Stockholm, Sweden

来源：

PHARMACOGENETICS | 1999年 / 9卷 / 05期

关键词：

debrisoquine; gene amplification; gene duplication; ultrarapid metabolism;

D O I：

10.1097/00008571-199910000-00013

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：657 / 660

页数：4

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