Highly stereoselective coupling reaction of acrolein or vinyl ketone with aldehydes

被引：56

作者：

Uehira, S ^{[1
]}

Han, ZF ^{[1
]}

Shinokubo, H ^{[1
]}

Oshima, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 09期

关键词：

D O I：

10.1021/ol990934w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Treatment of acrolein with a TiCL4-n-Bu(4)Nl mixed reagent in the presence of 2 equiv of aldehydes provided 4-hydroxy-1,3-dioxane derivatives in good yields with high stereoselectivities. The use of vinyl ketones instead of acrolein afforded aldo-type adducts with high syn selectivities.

引用

页码：1383 / 1385

页数：3

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