Reversible molecular adsorption based on multiple-point interaction by shrinkable gels

被引:176
作者
Oya, T [1 ]
Enoki, T
Grosberg, AY
Masamune, S
Sakiyama, T
Takeoka, Y
Tanaka, K
Wang, GQ
Yilmaz, Y
Feld, MS
Dasari, R
Tanaka, T
机构
[1] MIT, Dept Phys, Cambridge, MA 02139 USA
[2] MIT, Ctr Mat Sci & Engn, Cambridge, MA 02139 USA
[3] MIT, Dept Chem, Cambridge, MA 02139 USA
[4] MIT, George R Harrison Spect Lab, Cambridge, MA 02139 USA
关键词
D O I
10.1126/science.286.5444.1543
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A general approach is presented for creating polymer-gels that can recognize and capture a target molecule by multiple-point interaction and that can reversibly change their affinity to the target by more than one order of magnitude. The polymers consist of majority monomers that make the gel reversibly swell and shrink and minority monomers that constitute multiple-point adsorption centers for the target molecule, Multiple-point interaction is experimentally proven by power Laws found between the affinity and the concentration of the adsorbing monomers within the gels.
引用
收藏
页码:1543 / 1545
页数:3
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