Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines

被引：19

作者：

Beyreuther, K

Multhaup, G

Monning, U

Sandbrink, R

Beher, D

Hesse, L

Small, DH

Masters, CL

机构：

[1] UNIV MELBOURNE,DEPT PATHOL,PARKVILLE,VIC 3052,AUSTRALIA

[2] MENTAL HLTH RES INST,PARKVILLE,VIC 3052,AUSTRALIA

来源：

NEUROBIOLOGY OF ALZHEIMER'S DISEASE | 1996年 / 777卷

关键词：

D O I：

10.1111/j.1749-6632.1996.tb34403.x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We have identified and characterized the ligand binding properties of the Alzheimer's disease (AD) beta A4 amyloid protein precursor (APP), mapped the APP ligand binding sites and analyzed the regulation of APP expression, biogenesis and metabolism by components of the extracellular matrix (ECM) and cytokines.

引用

页码：74 / 76

页数：3

共 17 条

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[8] EXTRACELLULAR-MATRIX INFLUENCES THE BIOGENESIS OF AMYLOID PRECURSOR PROTEIN IN MICROGLIAL CELLS
MONNING, U
SANDBRINK, R
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