Advanced oxidation protein products (AOPP) and high-sensitive C-reactive protein (hs-CRP) in an "atheroma-free model": Down's syndrome

被引:15
作者
Goi, G.
Baquero-Herrera, C.
Licastro, F.
Dogliotti, G.
Corsi, M. M. [1 ]
机构
[1] Univ Milan, Clin Pathol Lab, Inst Gen Pathol, Milan, Italy
[2] Univ Milan, Dept Med Chem, Milan, Italy
[3] Univ Bologna, Immunol Sect, Dept Expt Pathol, Bologna, Italy
关键词
Down syndrome; AOPP-CRP; atherosclerosis;
D O I
10.1016/j.ijcard.2005.10.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Murdoch et al. in 1977 called Down syndrome an "atheroma-free model." In this preliminary study, we investigated advanced oxidation protein products (AOPP) ami high-sensitive C-reactive protein (hs-CR-P) in 47 age-matched Down syndrome patients and 20 age-matched healthy controls. In these healthy patients, we detected no new biochemical risk factors for atherosclerosis, such as AOPP and hs-CR-P, so risks are probably considerably lower. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:427 / 429
页数:3
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