Non-canonical Wnt signalling and regulation of gastrulation movements

被引：169

作者：

Tada, M

Concha, ML

Heisenberg, CP

机构：

[1] UCL, Dept Anat & Dev Biol, London WC1E 6BT, England

[2] Univ Chile, Fac Med, Inst Ciencias Biomed, Programa Morfol, Santiago 7, Chile

[3] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2002年 / 13卷 / 03期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

Wnt; convergent extension; planar polarity; zebrafish; Xenopus;

D O I：

10.1016/S1084-9521(02)00052-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, Patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements.

引用

页码：251 / 260

页数：10

共 76 条

[1] Frizzled signaling and cell-cell interactions in planar polarity [J].