Predictive Value of Mild Cognitive Impairment for Dementia The Influence of Case Definition and Age

被引：71

作者：

Baars, M. A. E. ^{[1
]}

van Boxtel, M. P. J. ^{[1
]}

Dijkstra, J. B. ^{[1
]}

Visser, P. J. ^{[1
,3
]}

van den Akker, M. ^{[2
]}

Verhey, F. R. J. ^{[1
]}

Jolles, J. ^{[1
]}

机构：

[1] Maastricht Univ, Sch Publ Hlth & Primary Care CAPHRI, Fac Hlth Med & Life Sci, Dept Psychiat & Neuropsychol, NL-6200 MD Maastricht, Netherlands

[2] Maastricht Univ, Sch Publ Hlth & Primary Care CAPHRI, Fac Hlth Med & Life Sci, Dept Gen Practice, NL-6200 MD Maastricht, Netherlands

[3] Vrije Univ Amsterdam Med Ctr, Dept Neurol, Amsterdam, Netherlands

来源：

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2009年 / 27卷 / 02期

关键词：

Dementia; Age; Cognition; Mild cognitive impairment; Population-based study; SUBJECTIVE MEMORY COMPLAINTS; NORMATIVE DATA; ALZHEIMERS-DISEASE; POPULATION; PERFORMANCE; EDUCATION; CRITERIA; SEX; CLASSIFICATION; VALIDATION;

D O I：

10.1159/000200465

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background/Aims: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of age on the predictive values was investigated. Methods: This study was conducted as part of an ongoing longitudinal study into the determinants of cognitive aging, the Maastricht Aging Study. Results: MCI best predicted dementia when multiple cognitive domains were considered and subjective complaints were not (sensitivity: 0.66, specificity: 0.78). Age had a strong influence on the sensitivity of MCI for dementia (age 60-70 years: sensitivity = 0.56; age 70-85 years: sensitivity = 0.70). Conclusion: The inclusion of multiple cognitive domains and participants aged 70 years and older leads to the best prediction of dementia, regardless of subjective complaints. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：173 / 181

页数：9

共 38 条

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