Identifying Sarcopenia in Acute Care Setting Patients

被引:85
作者
Rossi, Andrea P. [1 ]
Fantin, Francesco [1 ]
Micciolo, Rocco [2 ]
Bertocchi, Monica [1 ]
Bertassello, Paolo [1 ]
Zanandrea, Valeria [1 ]
Zivelonghi, Alessandra [1 ]
Bissoli, Luisa [1 ]
Zamboni, Mauro [1 ]
机构
[1] Univ Verona, Dept Med, Div Geriatr, I-37126 Verona, Italy
[2] Univ Trento, Dept Stat, Trento, Italy
关键词
Sarcopenia; walking speed; muscle strength; OLDER-ADULTS; MOBILITY; PREVALENCE; STRENGTH; RISK; MASS; DEFINITIONS; PREDICTION; DISABILITY; DIAGNOSIS;
D O I
10.1016/j.jamda.2013.11.018
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Objectives: To evaluate the prevalence of sarcopenia by applying European Working Group on Sarcopenia in Older People (EWGSOP) flow chart in an acute care geriatric unit as well as to test a modified version of the EWGSOP diagnostic algorithm combining handgrip and gait speed test to identify subjects with low muscle mass. Design: Observational cohort study. Setting: Geriatric unit in an academic medical department. Participants: One hundred nineteen acutely ill persons (34.4% female), with mean age 80.4 +/- 6.9 years and body mass index 26.3 +/- 4.9 kg/m(2). Measurements: Assessment of muscle mass by bioimpedence analysis, muscle strength by handheld dynamometer, and gait speed with the 4-meter walking test. Results: Using the EWGSOP classification for sarcopenia, 5.0% presented with sarcopenia and 21.0% with severe sarcopenia. Combining gait speed test and handgrip strength measurement, the highest predictive power in detecting subjects with low muscle mass was observed (sensitivity and specificity, 80.6% and 62.5%, respectively). Subjects presenting with both normal gait speed and handgrip showed normal values of muscle mass as assessed with bioimpedence analysis. By using the ROC method, when the 2 tests were combined, the AUC was statistically higher than when using each test separately (0.740; P = .018). Conclusions: Our study shows that 1 of 4 patients admitted to the acute care department were recognized to be sarcopenic. When a modifived version of the EWGSOP flow chart, obtained combining both gait speed and handgrip was used, sensitivity and specificity of algorithm to identify subjects with low muscle mass was improved. (C) 2014 - American Medical Directors Association, Inc. All rights reserved.
引用
收藏
页码:303.e7 / 303.e12
页数:6
相关论文
共 33 条
[1]
[Anonymous], 2011, R: A Language and Environment for Statistical Computing
[2]
Epidemiology of sarcopenia among the elderly in New Mexico [J].
Baumgartner, RN ;
Koehler, KM ;
Gallagher, D ;
Romero, L ;
Heymsfield, SB ;
Ross, RR ;
Garry, PJ ;
Lindeman, RD .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1998, 147 (08) :755-763
[3]
Bosaeus I, 2013, CLIN NUTR IN PRESS
[4]
Prevalence of sarcopenia estimated using a bioelectrical impedance analysis prediction equation in community-dwelling elderly people in Taiwan [J].
Chien, Meng-Yueh ;
Huang, Ta-Yi ;
Wu, Ying-Tai .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2008, 56 (09) :1710-1715
[5]
Sarcopenia: European consensus on definition and diagnosis [J].
Cruz-Jentoft, Alfonso J. ;
Baeyens, Jean Pierre ;
Bauer, Juergen M. ;
Boirie, Yves ;
Cederholm, Tommy ;
Landi, Francesco ;
Martin, Finbarr C. ;
Michel, Jean-Pierre ;
Rolland, Yves ;
Schneider, Stephane M. ;
Topinkova, Eva ;
Vandewoude, Maurits ;
Zamboni, Mauro .
AGE AND AGEING, 2010, 39 (04) :412-423
[6]
Longitudinal study of muscle strength, quality, and adipose tissue infiltration [J].
Delmonico, Matthew J. ;
Harris, Tamara B. ;
Visser, Marjolein ;
Park, Seok Won ;
Conroy, Molly B. ;
Velasquez-Mieyer, Pedro ;
Boudreau, Robert ;
Manini, Todd M. ;
Nevitt, Michael ;
Newman, Anne B. ;
Goodpaster, Bret H. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2009, 90 (06) :1579-1585
[7]
COMPARING THE AREAS UNDER 2 OR MORE CORRELATED RECEIVER OPERATING CHARACTERISTIC CURVES - A NONPARAMETRIC APPROACH [J].
DELONG, ER ;
DELONG, DM ;
CLARKEPEARSON, DI .
BIOMETRICS, 1988, 44 (03) :837-845
[8]
Sarcopenia Definitions Considering Body Size and Fat Mass Are Associated With Mobility Limitations: The Framingham Study [J].
Dufour, Alyssa B. ;
Hannan, Marian T. ;
Murabito, Joanne M. ;
Kiel, Douglas P. ;
McLean, Robert R. .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2013, 68 (02) :168-174
[9]
Cachexia: A new definition [J].
Evans, William J. ;
Morley, John E. ;
Argiles, Josep ;
Bales, Connie ;
Baracos, Vickie ;
Guttridge, Denis ;
Jatoi, Aminah ;
Kalantar-Zadeh, Kamyar ;
Lochs, Herbert ;
Mantovani, Giovanni ;
Marks, Daniel ;
Mitch, William E. ;
Muscaritoli, Maurizio ;
Najand, Armine ;
Ponikowski, Piotr ;
Rossi Fanelli, Filippo ;
Schambelan, Morrie ;
Schols, Annemie ;
Schuster, Michael ;
Thomas, David ;
Wolfe, Robert ;
Anker, Stefan D. ;
Boyce, Amanda ;
Nuckolls, Glen .
CLINICAL NUTRITION, 2008, 27 (06) :793-799
[10]
An introduction to ROC analysis [J].
Fawcett, Tom .
PATTERN RECOGNITION LETTERS, 2006, 27 (08) :861-874