The pubertal spurt: Effects of sex steroids on growth hormone and insulin-like growth factor I

被引：17

作者：

Caufriez, A

机构：

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1997年 / 71卷 / 02期

关键词：

growth hormone; insulin-like growth factor I; oestrogens; pubertal spurt; testosterone;

D O I：

10.1016/S0301-2115(96)02638-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In puberty, the growth spurt and the appearance of secondary sex characteristics occur concomitantly with an increase of sex steroids, growth hormone (GH) and insulin-like growth factor I (IGF-I). A number of experiments indicate that sex steroids exert a stimulatory action on the somatotropic axis. This effect is due to an amplifying action of oestradiol (secreted by the ovaries dr after testosterone aromatization) on the neuroendocrine regulation of pulsatile GH release. (C) 1997 Elsevier Science Ireland Ltd.

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页码：215 / 217

页数：3

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