An NMR-based metabolomic approach to assess metabolism in splanchnic tissues of steers

被引：2

作者：

Bertram, HC

Kristensen, NB

Malmendal, A

Nielsen, NC

Jensen, SK

Harmon, DL

机构：

[1] Danish Inst Agr Sci, Dept Anim Physiol & Nutr, DK-8830 Tjele, Denmark

[2] Danish Inst Agr Sci, Dept Food Sci, DK-8830 Tjele, Denmark

[3] Aarhus Univ, Dept Chem, Interdisciplinary Nanosci Ctr, iNANO, DK-8000 Aarhus C, Denmark

[4] Univ Kentucky, Dept Anim Sci, Lexington, KY 40546 USA

来源：

JOURNAL OF ANIMAL AND FEED SCIENCES | 2004年 / 13卷

关键词：

NMR; metabolomics; splanchnic; metabolism; steer; plasma;

D O I：

10.22358/jafs/73921/2004

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

H-1 NMR spectra were acquired on plasma samples obtained from the mesenteric artery, hepatic portal vein and the hepatic vein of steers (n=6) to demonstrate a NMR-based metabolomic approach to study splanchnic metabolism. The metabolic differences between the different plasma samples (arterial, portal, hepatic) were examined by partial least square regressions (PLSR) on the obtained spectra. These analyses revealed spectral differences that could be ascribed to changes in the level of propionate, beta-hydroxybutyrate, lactate, acetate, n-butyrate and glucose, which was supported by biochemical analyses.

引用

页码：295 / 298

页数：4