Analytical interference in determination of procalcitonin by PCT-Q® (Brahms®)

被引：4

作者：

Desideri-Vaillant, C. ^{[1
]}

Rouby, Y.

Cardon, N.

Vinsonneau, U.

Laborde, J. -P.

机构：

[1] HIA Clermont Tonnerre, Federat Biol Clin, F-29240 Brest, France

[2] HIA Clermont Tonnerre, Serv Cardiol, F-29240 Brest, France

[3] HIA Clermont Tonnerre, Serv Med Interne Oncol & Pathol Infect, F-29240 Brest, France

来源：

PATHOLOGIE BIOLOGIE | 2006年 / 54卷 / 05期

关键词：

procalcitonin; evaluation study; heterophil human antimouse antibody;

D O I：

10.1016/j.patbio.2005.10.001

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Procalcitonin (PCT) is a biological marker of infection. We present the cas of a patient who has presented a high concentration of PCT with PCT-Q((R)) test (Brahmso). At the same time, the concentration of CRP is remained low, which is no physiological. Then, PCT concentration has been determinated with an automatic system (Kryptor((R))-Brahms((R))) and finded at low than 0.5 mu g/l. Brahms((R)) company has searched an analytical interference: human anti-mouse antibodies (HAMA) were positive. If PCT concentration stay a marker of infection for the most part, this case show that biologists have to keep in mind that immunological assays remain submitted to interferences. (c) 2006 Elsevier SAS. Tous droits reserves.

引用

页码：293 / 295

页数：3