SAP family proteins

被引:80
作者
Fujita, A [1 ]
Kurachi, Y [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Dept Pharmacol 2, Osaka 5650871, Japan
关键词
D O I
10.1006/bbrc.1999.1893
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Thus far, five members including Dlg, SAP97/hDlg, SAP90/PSD-95, SAP102, and PSD-93/chapsyn110 which belong to SAP family have been identified. Recent studies have revealed that these proteins play important roles in the localization and function of glutamate receptors and K+ channels. Although most of them have been reported to be localized to the synapse, only one member, SAP97, is expressed also in the epithelial cells. In this review, we have summarized structural characters of SAP family proteins and discuss their functions in neurons and epithelial cells. (C) 2000 Academic Press.
引用
收藏
页码:1 / 6
页数:6
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