aquaporins;
medicinal chemistry;
membrane proteins;
Nobel lecture;
protein structures;
D O I:
10.1002/anie.200460804
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Water is the most important component of all organisms and is the basis of all life. That water can pass through cell membranes has long been known-but how is the selective transport of water molecules achieved without concommitent diffusion of H3O+ ions? Peter Agre received the 2003 Nobel Prize in Chemistry for the discovery and investigation of the membrane proteins responsible, namely, the aquaproteins.