Currently, there is little information on the results of reimplantation after previous resection for an infected shoulder arthroplasty. The purpose of this study was to determine the rate of recurrent infection and clinical results. Between 1975 and 2000, 4 patients with a resection arthroplasty from a previously infected shoulder orthroplasty underwent subsequent reimplantation of a prosthesis. The time interval from resection arthroplasty to reimplantation ranged from 7 months to 5.5 years. The mean clinical follow-up was 7.4 years (range, 2-15 years). There were no patients with recurrent infection. At the most recent follow-up, 2 patients had no pain, 1 had slight pain, and 1 had moderate pain, Mean elevation improved from 60degrees to 80degrees, and external rotation improved from 13degrees to 50degrees. With regard to patient satisfaction, 1 patient was much better, 2 were better, and 1 was the some. There were 2 satisfactory results and 2 unsatisfactory results. Reimplantation of a shoulder arthroplasty after a previous resection arthroplasty for infection can be performed with a low risk of reinfection. However, arthroplasty in this setting is especially challenging because of the potential for significant bone and soft-tissue deficits. These challenges can compromise the clinical results.