Electron and atomic force microscopy of membrane proteins

被引：32

作者：

Heymann, JB ^{[1
]}

Muller, DJ ^{[1
]}

Mitsuoka, K ^{[1
]}

Engel, A ^{[1
]}

机构：

[1] KYOTO UNIV, FAC SCI, DEPT BIOPHYS, KYOTO 60601, JAPAN

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 04期

关键词：

D O I：

10.1016/S0959-440X(97)80120-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electron crystallography is becoming a powerful tool for the resolution of membrane protein structures. The past year has seen the production of a bacteriorhodopsin model at 3.5 Angstrom and the structure of aquaporin 1 approaching atomic resolution. Determination of surface topographies of 2D crystals using the atomic force microscope is similarly advancing to a level that reveals submolecular details. As the latter is operated in solution, membrane proteins can be observed at work.

引用

页码：543 / 549

页数：7

共 66 条

[1] Three-dimensional structure of bovine cytochrome bc(1) complex by electron cryomicroscopy and helical image reconstruction
Akiba, T
Toyoshima, C
Matsunaga, T
Kawamoto, M
Kubota, T
Fukuyama, K
Namba, K
Matsubara, H
[J]. NATURE STRUCTURAL BIOLOGY, 1996, 3 (06): : 553 - 561
[2] STRUCTURAL-ANALYSIS OF AT MIP FAMILY PROTEIN FROM THE DIGESTIVE-TRACT OF CICADELLA-VIRIDIS
BEURON, F
LECAHEREC, F
GUILLAM, MT
CAVALIER, A
GARRET, A
TASSAN, JP
DELAMARCHE, C
SCHULTZ, P
MALLOUH, V
ROLLAND, JP
HUBERT, JF
GOURANTON, J
THOMAS, D
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (29) : 17414 - 17422
[3] BOSTTCHER B, 1995, FEBS LETT, V373, P262
[4] Three-dimensional organization of a human water channel
Cheng, AC
vanHoek, AN
Yeager, M
Verkman, AS
Mitra, AK
[J]. NATURE, 1997, 387 (6633) : 627 - 630
[5] CRYSTAL-STRUCTURES EXPLAIN FUNCTIONAL-PROPERTIES OF 2 ESCHERICHIA-COLI PORINS
COWAN, SW
SCHIRMER, T
RUMMEL, G
STEIERT, M
GHOSH, R
PAUPTIT, RA
JANSONIUS, JN
ROSENBUSCH, JP
[J]. NATURE, 1992, 358 (6389) : 727 - 733
[6] 2-D STRUCTURE OF THE NEUROSPORA-CRASSA PLASMA-MEMBRANE ATPASE AS DETERMINED BY ELECTRON CRYOMICROSCOPY
CYRKLAFF, M
AUER, M
KUHLBRANDT, W
SCARBOROUGH, GA
[J]. EMBO JOURNAL, 1995, 14 (09) : 1854 - 1857
[7] Projection structure of an invertebrate rhodopsin
Davies, A
Schertler, GFX
Gowan, BE
Saibil, HR
[J]. JOURNAL OF STRUCTURAL BIOLOGY, 1996, 117 (01) : 36 - 44
[8] CRYSTALLOGRAPHIC REFINEMENT AT 2.3-ANGSTROM RESOLUTION AND REFINED MODEL OF THE PHOTOSYNTHETIC REACTION-CENTER FROM RHODOPSEUDOMONAS-VIRIDIS
DEISENHOFER, J
EPP, O
SINNING, I
MICHEL, H
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1995, 246 (03) : 429 - 457
[9] The micelle to vesicle transition of lipids and detergents in the presence of a membrane protein: Towards a rationale for 2D crystallization
Dolder, M
Engel, A
Zulauf, M
[J]. FEBS LETTERS, 1996, 382 (1-2): : 203 - 208
[10] SHAPE TRANSFORMATIONS IN THE LECITHIN BILE-SALT SYSTEM - FROM CYLINDERS TO VESICLES
EGELHAAF, SU
SCHURTENBERGER, P
[J]. JOURNAL OF PHYSICAL CHEMISTRY, 1994, 98 (34) : 8560 - 8573

← 1 2 3 4 5 6 7 →