HIV and hypogonadism: a new challenge for young-aged and middle-aged men on effective antiretroviral therapy

被引：19

作者：

Lachatre, Marie ^{[1
,2
,3
]}

Pasquet, Armelle ^{[3
]}

Ajana, Faiza ^{[3
]}

Soudan, Benoit ^{[4
]}

Lion, Georges ^{[5
]}

Bocket, Laurence ^{[6
]}

Cornavin, Pauline ^{[3
]}

Senneville, Eric ^{[3
]}

Boufassa, Faroudy ^{[7
]}

Cheret, Antoine ^{[3
,8
,9
]}

机构：

[1] Bichat Claude Bernard Hosp, AP HP, Dept Infect Dis, Paris, France

[2] Paris Diderot Univ, Sorbonne Paris Cite, Paris, France

[3] Tourcoing Hosp, Dept Infect Dis, Tourcoing, France

[4] Lille Hosp, Biochem Lab, Lille, France

[5] Lille Hosp, Dept Nucl Med, Lille, France

[6] Lille Hosp, Virol Lab, Lille, France

[7] Paris Saclay Univ, Univ Paris Sud, UVSQ, INSERM,CESP U1018, Paris, France

[8] Hop Bicetre, AP HP, Dept Internal Med, Le Kremlin Bicetre, France

[9] Paris Descartes Univ, EA 7327, Paris, France

来源：

AIDS | 2017年 / 31卷 / 03期

关键词：

HUMAN-IMMUNODEFICIENCY-VIRUS; FREE TESTOSTERONE; ANDROGEN DEFICIENCY; OLDER MEN; PREVALENCE; INFECTION; ENDOCRINE; SERUM; HORMONES; RISK;

D O I：

10.1097/QAD.0000000000001348

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Male hypogonadism is poorly defined in people living with HIV. Using a reliable free-testosterone assay, we examined the prevalence and risk factors of male hypogonadism among people living with HIVon effective antiretroviral therapy. Male hypogonadism was found in 12.4% of patients, twice the rate reported in the general population of the same age. Two risk thresholds, namely 5 years of antiretroviral therapy and 19% total body fat, may help to identify patients at risk. © Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：451 / 453

页数：3

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