Studies on in vivo antitussive activity of Leucas lavandulaefolia using a cough model induced by sulfur dioxide gas in mice

被引：19

作者：

Saha, K ^{[1
]}

Mukherjee, PK ^{[1
]}

Murugesan, T ^{[1
]}

Saha, BP ^{[1
]}

Pal, M ^{[1
]}

机构：

[1] JADAVPUR UNIV,FAC ENGN & TECHNOL,DEPT PHARMACEUT TECHNOL,CALCUTTA 700032,W BENGAL,INDIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1997年 / 57卷 / 02期

关键词：

Leucas lavandulaefolia; antitussive; sulfur dioxide; cough; methanol extract;

D O I：

10.1016/S0378-8741(97)00050-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The methanol extract of Leucas lavandulaefolia was investigated for its effects on a cough model induced by sulfur dioxide gas in mice. It exhibited significant antitussive activity when compared with control in a dose-dependent manner. The antitussive activity of the extract was comparable to that of codeine phosphate (10 mg/kg), a prototype antitussive agent. The Leucas lavandulaefolia extract at 100, 200, and 400 mg/kg. p.o. showed inhibition of cough by 35.0, 51.9, and 56.5% within 1 h of performing the experiment. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：89 / 92

页数：4