Anti-CD20 chimeric monoclonal antibody (rituximab) for the treatment of recalcitrant, life-threatening pemphigus vulgaris with implications in the pathogenesis of the disorder

被引：94

作者：

Salopek, TG ^{[1
]}

Logsetty, S

Tredget, EE

机构：

[1] Univ Alberta, Div Dermatol & Cutaneous Sci, Edmonton, AB T6G 2E1, Canada

[2] Univ Alberta, Firefighters Burn Treatment Unit, Edmonton, AB, Canada

[3] Univ Alberta, Dept Surg, Edmonton, AB, Canada

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2002年 / 47卷 / 05期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1067/mjd.2002.126273

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Rituximab, a chimeric monoclonal antibody directed against CD20 of B cells, has been reported to be effective in the treatment of B-cell lymphomas and malignant and nonmalignant plasma cell-dependent diseases. We describe a 30-year-old woman with refractory pemphigus vulgaris who experienced a partial remission after treatment with rituximab.

引用

页码：785 / 788

页数：4

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