Fluorescent pyrophosphate sensor with high selectivity over ATP in water

被引：353

作者：

Lee, DH

Kim, SY

Hong, JI ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Seoul 151747, South Korea

[2] Korea Adv Inst Sci & Technol, Ctr Mol Design & Synth, Taejon 305701, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 36期

关键词：

binuclear complexes; fluorescent probes; molecular recognition; pyrophosphates; zinc;

D O I：

10.1002/anie.200453914

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

High affinity and selective detection for PPi is exhibited by a new fluorescent sensor based on a naphthalene-dpa system (see picture). The binuclear zinc complex is remarkably selective toward PPi over other anions. For example, PPi can be detected at micromolar concentrations in the presence of a large excess of ATP. PPi = pyrophosphate, ATP = adenosine triphosphate, dpa = bis(2-pyridyl-methyl)amine.

引用

页码：4777 / 4780

页数：4

共 51 条

[1]

[Anonymous], 2001, ANGEW CHEM, V113, P2710

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