A fluorescence detection and selection device for DNA-molecules, bound to microspheres

被引：7

作者：

Holm, J ^{[1
]}

Elderstig, H ^{[1
]}

Kristensen, O ^{[1
]}

Rigler, R ^{[1
]}

机构：

[1] IND MICROELECT CTR AB,S-16421 KISTA,SWEDEN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 5-6期

关键词：

D O I：

10.1080/07328319708002916

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A device for the detection and selection of DNA-molecules bound to microspheres has been realized. It is based on a quartz chip with a capillary flowsystem, and confocal fluorescence detection of DNA. The device is to be used to identify and isolate single DNA-molecules for sequencing experiments.

引用

页码：557 / 562

页数：6

共 7 条

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[2]

HARRISON DJ, IEEE INT C SOL STAT, P792

[3]

HOLM J, 1996, THESIS KAROLINSKA I

[4]

KAPLAN W, 1994, IEEE MICRO ELECTRO M

[5]

Mets U, 1994, J Fluoresc, V4, P259, DOI 10.1007/BF01878461

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RIGLER, R .

JOURNAL OF BIOTECHNOLOGY, 1995, 41 (2-3) :177-186

[7]

SOPER SA, 1991, P SOC PHOTO-OPT INS, V1435, P168, DOI 10.1117/12.44241

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