Biodegradable controlled release glass in the repair of peripheral nerve injuries

被引：17

作者：

Lenihan, DV ^{[1
]}

Carter, AJ ^{[1
]}

Gilchrist, T ^{[1
]}

Healy, DM ^{[1
]}

Miller, LM ^{[1
]}

Glasby, MA ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Med, Dept Clin Neurosci, Western Gen Hosp, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME | 1998年 / 23B卷 / 05期

关键词：

D O I：

10.1016/S0266-7681(98)80007-7

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

The experiments in this paper were concerned with the recovery of function and ease of application of an entubulation technique using a biodegradable, controlled release glass tube (CRG) for the repair of a transected peripheral nerve. The peroneal nerves of 15 New Zealand White rabbits were repaired with either a CRC tube filled with freeze-thawed muscle, or a conventional freeze thawed muscle graft (FTMG), These mere compared with controls in which a CRG was used to enclose the cut ends of a nerve separated by a 1 cm gap, Electrophysiological and morphometric assessment was carried out 6 months after repair. No statistical difference was found in any test between the FTMG and the CRG tube filled with freeze thawed muscle. The CRG tube and I cm gap produced inferior levels of recovery of function when compared with the other two repair groups.

引用

页码：588 / 593

页数：6

共 22 条

[1] A COLLAGEN-BASED NERVE GUIDE CONDUIT FOR PERIPHERAL-NERVE REPAIR - AN ELECTROPHYSIOLOGICAL STUDY OF NERVE REGENERATION IN RODENTS AND NONHUMAN-PRIMATES [J].