LAT Polices T Cell Activation

被引：9

作者：

Brownlie, Rebecca ^{[1
]}

Zamoyska, Rose ^{[1
]}

机构：

[1] Univ Edinburgh, Inst Immunol & Infect Res, Edinburgh EH9 3JT, Midlothian, Scotland

来源：

IMMUNITY | 2009年 / 31卷 / 02期

关键词：

INHIBITORY FUNCTION; TOLERANCE; ZAP-70;

D O I：

10.1016/j.immuni.2009.08.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Mutations in the adaptor molecule LAT can lead to autoimmunity. In this issue of Immunity, Mingueneau et al. (2009) describe how this may not be a failure of central tolerance.

引用

页码：174 / 176

页数：3

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