The reaction of hydroxylamine with aryl trifluoromethyl-β-diketones:: Synthesis of 5-hydroxy-5-trifluoromethyl-Δ2-isoxazolines and their dehydration to 5-trifluoromethylisoxazoles

被引：53

作者：

Kumar, Vinod ^{[1
]}

Aggarwal, Ranjana ^{[1
]}

Singh, Shiv P. ^{[1
]}

机构：

[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2006年 / 127卷 / 07期

关键词：

trifluoromethylisoxazolines; trifluoromethylisoxazoles; NMR spectroscopy; fluorinated-beta-diketones; fluorinated diazodiketones;

D O I：

10.1016/j.jfluchem.2006.03.009

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

Reaction of hydroxylamine hydrochloride with aryl trifluoromethyl-beta-diketones affords 5-hydroxy-5-trifluoromethyl-Delta 2 -isoxazolines rather than the reported 3-trifluoromethylisoxazoles. The structural assignment is based on the analysis of their NMR (H-1, C-13 and F-19) spectral data and of their dehydration products, 5-trifluoromethylisoxazoles. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：880 / 888

页数：9

共 37 条

[1]

ISOXAZOLE ANTHELMINTICS [J].