Ceramide in apoptosis:: A revisited role

被引:49
作者
Levade, T [1 ]
Malagarie-Cazenave, S [1 ]
Gouazé, V [1 ]
Ségui, B [1 ]
Tardy, C [1 ]
Betito, S [1 ]
Andrieu-Abadie, N [1 ]
Cuvillier, O [1 ]
机构
[1] CHU Rangueil, Biochim Lab, INSERM, U466, F-31403 Toulouse 4, France
关键词
apoptosis; ceramide; FAN; sphingomyelin; sphingomyelinase; sphingosine;
D O I
10.1023/A:1020215815013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The sphingolipid ceramide has recently emerged as a new transducer or modulator of apoptotic cell death. This function, however, has recently been challenged. Here, in the light of recent observations, the role of ceramide in apoptosis signaling is discussed.
引用
收藏
页码:601 / 607
页数:7
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