Determination of chiral ratio of o,p-DDT and o,p-DDD pesticides on polysaccharides chiral stationary phases by HPLC under reversed-phase mode

被引：49

作者：

Ali, I ^{[1
]}

Aboul-Enein, HY ^{[1
]}

机构：

[1] King Faisal Specialist Hosp & Res Ctr, Biol & Med Res Dept MBC03, Pharmaceut Anal Lab, Riyadh 11211, Saudi Arabia

来源：

ENVIRONMENTAL TOXICOLOGY | 2002年 / 17卷 / 04期

关键词：

chiral resolution; o; p-DDT; p-DDD; pesticides; Chiralpak AD-R; Chiralcel OD-R; Chiralcel OJ-R;

D O I：

10.1002/tox.10069

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 [工学]; 0830 [环境科学与工程];

摘要：

A simple and reliable HPLC method for the chiral resolution of o,p-DDT and o,p-DDD is described. The enantiomeric resolution of o,p-DDT and o,p-DDD has been achieved on Chiralpak AD-R, Chiralcel OD-R, and Chiralcel OJ-R chiral stationary phases. The mobile phases used were acetonitrile-water (50:50 [v/v]) and acetonitrile-2-propanol (50:50 [v/v]) at a flow rate of 1.0 mL/min. For both pesticides detection was done at 220 nm. The values for o,p-DDT of alpha and R-s varied from 1.24 to 2.52 and from 0.80 to 2.47, respectively. The values of alpha and R-s for o,p-DDD were 1.26 and 0.60, respectively. (C) 2002 Wiley Periodicals, Inc.

引用

页码：329 / 333

页数：5

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