The real-time, three-dimensional analyses of benign and malignant skin tumors by confocal laser scanning microscopy

被引：15

作者：

Ono, Ichiro ^{[1
]}

Sakemoto, Akiko ^{[1
]}

Ogino, Jiro ^{[1
]}

Kamiya, Takafumi ^{[1
]}

Yamashita, Toshiharu ^{[1
]}

Jimbow, Kowichi ^{[1
]}

机构：

[1] Sapporo Med Univ, Sch Med, Dept Dermatol, Chuo Ku, Sapporo, Hokkaido 0608543, Japan

来源：

JOURNAL OF DERMATOLOGICAL SCIENCE | 2006年 / 43卷 / 02期

关键词：

skin tumors; clinico-pathological analysis; basal cell carcinoma; malignant melanoma; microstructure; multiplanar reconstruction;

D O I：

10.1016/j.jdermsci.2006.05.001

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

Background: In obtain images of skin tumors non-invasively with real-time, confocal laser scanning microscope (CLSM) is introduced. Objective: Reconstructed images of given horizontal sections were converted into three-dimensions using the data set of a large number of tomograms in the horizontal directions. Methods: To develop the multiplaner reconstruction images of skin tumors in vertical directions and three-dimensionally reconstructed images of tumors will be obtained from the continuously collected horizontal image data sets. Results: Three-dimensional analyses of the skin tumors from reconstructed images of the CLSM scanning have provided the information as to their physiological characteristics as well as the extent of deep invasion in real-time with non-invasive manner. High performance three-dimensional conversion software was effective in displaying three-dimensional construction of skin tumors. Conclusion: The CLSM scanning images followed by three-dimensional reconstruction using them can provide the real-time and non-invasive diagnoses of skin tumors and analyze the radial growth phase of tumors and the three-dimensional growth characteristics. (c) 2006 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

引用

页码：135 / 141

页数：7

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