Improved procedure for the oxidative cleavage of olefins by OsO4-NaIO4

被引：401

作者：

Yu, WS ^{[1
]}

Mei, Y ^{[1
]}

Kang, Y ^{[1
]}

Hua, ZM ^{[1
]}

Jin, ZD ^{[1
]}

机构：

[1] Univ Iowa, Coll Pharm, Div Med & Nat Prod Chem, Iowa City, IA 52242 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 19期

关键词：

D O I：

10.1021/ol0400342

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxidative cleavage of olefins by OsO4-NaIO4 Sometimes suffers from low yields due to the formation of side products. It is found that the addition of 2,6-lutidine can suppress the side reactions and dramatically improve the yield of this classic reaction.

引用

页码：3217 / 3219

页数：3

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