Coeliac disease: an update for pathologists

被引：201

作者：

Dickson, B. C.

Streutker, C. J.

Chetty, R.

机构：

[1] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON M4X 1K9, Canada

[2] St Michaels Hosp, Div Pathol, Toronto, ON M5B 1W8, Canada

来源：

JOURNAL OF CLINICAL PATHOLOGY | 2006年 / 59卷 / 10期

关键词：

D O I：

10.1136/jcp.2005.035345

中图分类号：

R36 [病理学];

学科分类号：

100104 [病理学与病理生理学];

摘要：

Coeliac disease is the manifestation of an immune hypersensitivity reaction towards gluten and related proteins, in genetically predisposed people. Although the precise pathogenesis of this condition remains to be fully elucidated, it is probably multifactorial in origin. The diagnosis of coeliac disease has traditionally depended on intestinal biopsies alone; nowadays, the diagnosis has been expanded to include an array of serological markers. This review is intended to offer pathologists an update of the relevant history and immunopathology pertaining to coeliac disease and also to offer recommendations on the ongoing responsibilities of the pathologist in the diagnosis and reporting of coeliac disease.

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页码：1008 / 1016

页数：9

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