Characterization and application of poly(β-hydroxyalkanoates) family as composite biomaterials

被引：161

作者：

Galego, N ^{[1
]}

Rozsa, C

Sánchez, R

Fung, J

Vázquez, A

Tomás, JS

机构：

[1] Univ Havana, Mat & Reagents Inst, Lab Polymers, Havana 10400, Cuba

[2] N Fluminense State Univ, Polymer Sect, Adv Mat Lab, Campos, RJ, Brazil

[3] Polytech Inst Jose Antonio Echevarria, Havana, Cuba

[4] Mar del Plata Natl Univ, INTEMA, Mar Del Plata, Buenos Aires, Argentina

[5] Res Inst Sugar Cane Derivat, Lab Chromatog, Havana, Cuba

来源：

POLYMER TESTING | 2000年 / 19卷 / 05期

关键词：

D O I：

10.1016/S0142-9418(99)00011-2

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Some polyhydroxyalkanoates (PHA), polyhydroxybutyrate (PHB) and copolymers poly(hydroxybutyrs co-hydroxyvalerate) (P(HB-co-HV)), were characterized by different techniques (GPC, DSC, DMA, FT DRX) in order to be used in hydroxyapatite (HA) composites. These polymers presented high molecu weights and are semicrystalline materials. The crystallinity has a slight tendency to decrease with increasing HV content in the copolymer, PHA/HA composites prepared at the same composition, show a lower elastic modulus than 0 and 8% HV content. The composite P(HB-co-8%HV)/HA (30% w/w) 1 the highest modulus. In addition, this composite has a mechanical strength in compression of 62 M which is about the same order of magnitude of several human bones and thus it is interesting as biomater for use in fracture fixation, (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：485 / 492

页数：8

共 17 条

[1] STUDIES OF COMPOSITION AND CRYSTALLINITY OF BACTERIAL POLY(BETA-HYDROXYBUTYRATE-CO-BETA-HYDROXYVALERATE) [J].

BLOEMBERGEN, S ;

HOLDEN, DA ;

HAMER, GK ;

BLUHM, TL ;

MARCHESSAULT, RH .

MACROMOLECULES, 1986, 19 (11) :2865-2871

[2] ISODIMORPHISM IN BACTERIAL POLY(BETA-HYDROXYBUTYRATE-CO-BETA-HYDROXYVALERATE) [J].

BLUHM, TL ;

HAMER, GK ;

MARCHESSAULT, RH ;

FYFE, CA ;

VEREGIN, RP .

MACROMOLECULES, 1986, 19 (11) :2871-2876

[3] Miscibility of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and poly(vinyl chloride) blends [J].

Choe, S ;

Cha, YJ ;

Lee, HS ;

Yoon, JS ;

Choi, HJ .

POLYMER, 1995, 36 (26) :4977-4982

[4]

Doi Y, 1990, MICROBIAL POLYESTERS, P107

[5] THE MECHANICAL-PROPERTIES OF A THERMOPLASTIC ELASTOMER PRODUCED BY THE BACTERIUM PSEUDOMONAS-OLEOVORANS [J].

GAGNON, KD ;

LENZ, RW ;

FARRIS, RJ ;

FULLER, RC .

RUBBER CHEMISTRY AND TECHNOLOGY, 1992, 65 (04) :761-777

[6]

GALEGO N, 1996, POLYM B, V37, P429

[7]

GONZALEZ R, 1992, MAT BIOACTIVOS IMPLA, P1

[8] Single crystals and crystalline morphology of synthetic racemic poly(beta-hydroxybutyrate) [J].

Hocking, PJ ;

Revol, JF ;

Marchessault, RH .

MACROMOLECULES, 1996, 29 (07) :2467-2471

[9]

Holmes P.A., 1988, DEV CRYSTALLINE POLY, V2, P1, DOI DOI 10.1007/978-94-009-1341-71.

[10] Association equilibria and miscibility prediction in blends of poly(vinylphenol) with poly(hydroxybutyrate) and related homo- and copolymers: An FTIR study [J].

Iriondo, P ;

Iruin, JJ ;

FernandezBerridi, MJ .

MACROMOLECULES, 1996, 29 (17) :5605-5610

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