Calcium phosphate cements as bone drug delivery systems: A review

被引：517

作者：

Ginebra, M. P. ^{[1
]}

Traykova, T. ^{[1
]}

Planell, J. A. ^{[1
]}

机构：

[1] Tech Univ Catalonia, Dept Mat Sci & Met Engn, Biomed Engn Res Ctr, Div Biomat Biomech & Tissue Engn, Barcelona 08028, Spain

来源：

JOURNAL OF CONTROLLED RELEASE | 2006年 / 113卷 / 02期

关键词：

D O I：

10.1016/j.jconrel.2006.04.007

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Since calcium phosphate cements were proposed, several formulations have been developed, some of them commercialised, and they have proven to be very efficient bone substitutes in different applications. Some of their properties, such as the injectability, or the low-temperature setting, which allows the incorporation of different drugs, make them very attractive candidates as drug carriers. In this article, the performance of calcium phosphate cements as carriers of different types of drugs, such as antibiotics, analgesics, anticancer, anti-inflammatory, as well as growth factors is reviewed. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：102 / 110

页数：9

共 77 条

[1]

[Anonymous], 2004, Biomaterials Science-An Introduction to Materials in Medicine

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