The interleukin-1 receptor antagonist gene: a single-copy variant of the intron 2 variable number tandem repeat (VNTR) polymorphism

被引：47

作者：

Vamvakopoulos, JE

Taylor, CJ

Morris-Stiff, GJ

Green, C

Metcalfe, S

机构：

[1] Univ Cambridge, Dept Surg, Cambridge, England

[2] Addenbrookes Hosp NHS Trust, Tissue Typing Lab, Cambridge, England

[3] Univ Wales Coll Cardiff, Sch Med, Cardiff CF1 3NS, S Glam, Wales

[4] Northwick Pk Inst Med Res, Harrow, Middx, England

来源：

EUROPEAN JOURNAL OF IMMUNOGENETICS | 2002年 / 29卷 / 04期

关键词：

D O I：

10.1046/j.1365-2370.2002.00319.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A variable number tandem repeat (VNTR) polymorphism exists within intron 2 of the human interleukin-1 receptor antagonist gene, consisting of perfect repeats of an 86-bp sequence. Five allelic variants have been identified wherein the number of repeats varies from two to six. This is the first report of a rare, single-copy allele designated IL1RN*0.

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页码：337 / 340

页数：4

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