CD57+ cells in radicular cyst

被引：27

作者：

Moreira, PR

Santos, DFM

Martins, RD

Gomez, RS

机构：

[1] Univ Fed Minas Gerais, Fac Odontol, Sch Dent, Dept Oral Surg & Pathol, BR-30380030 Belo Horizonte, MG, Brazil

[2] Univ Fed Minas Gerais, Dept Restorat Dent, Sch Dent, BR-30380030 Belo Horizonte, MG, Brazil

来源：

INTERNATIONAL ENDODONTIC JOURNAL | 2000年 / 33卷 / 02期

关键词：

immunology; pathogenesis; pathology; radicular cyst;

D O I：

10.1046/j.1365-2591.2000.00276.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 [口腔医学];

摘要：

Aim As CD57 antigen is an important modulator of the immune system, the purpose of the present study was to compare the expression of this antigen on radicular cysts (RC) with hyperplastic or atrophic epithelium. Methodology Twenty cases of RC were retrieved and classified as atrophic or hyperplastic. A biotin-streptavidin amplified system was used for identification of the CD57 receptor. Results The results demonstrated a greater percentage of CD57(+) cells in RC with atrophic epithelium compared to hyperplastic epithelium, Conclusion As the expression of CD57 is indicative of immunosuppression, it may constitute a negative immunomodulator of RC's epithelium growth. Further studies are necessary to understand the importance of this cell to the biological activity or inactivity of RC's epithelium development.

引用

页码：99 / 102

页数：4

共 18 条

[1]

Arai K, 1998, CLIN EXP IMMUNOL, V111, P345

[2]

IMMUNOCYTOCHEMICAL LOCALIZATION OF INFLAMMATORY CYTOKINES AND VASCULAR ADHESION RECEPTORS IN RADICULAR CYSTS [J].

BANDO, Y ;

HENDERSON, B ;

MEGHJI, S ;

POOLE, S ;

HARRIS, M .

JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1993, 22 (05) :221-227

[3]

Human germinal center CD4(+)CD57(+) T cells act differently on B cells than do classical T-helper cells [J].

Bouzahzah, F ;

Bosseloir, A ;

Heinen, E ;

Simar, LJ .

DEVELOPMENTAL IMMUNOLOGY, 1995, 4 (03) :189-197

[4]

ANTIGEN UNMASKING ON FORMALIN-FIXED, PARAFFIN-EMBEDDED TISSUE-SECTIONS [J].

CATTORETTI, G ;

PILERI, S ;

PARRAVICINI, C ;

BECKER, MHG ;

POGGI, S ;

BIFULCO, C ;

KEY, G ;

DAMATO, L ;

SABATTINI, E ;

FEUDALE, E ;

REYNOLDS, F ;

GERDES, J ;

RILKE, F .

JOURNAL OF PATHOLOGY, 1993, 171 (02) :83-98

[5]

LANGERHANS CELLS IN APICAL PERIODONTAL CYSTS - AN IMMUNOHISTOCHEMICAL STUDY [J].

CONTOS, JG ;

CORCORAN, JF ;

LATURNO, SAL ;

CHIEGO, DJ ;

REGEZI, JA .

JOURNAL OF ENDODONTICS, 1987, 13 (02) :52-55

[6]

Immunohistochemical study of apical periodontal cysts [J].

Cury, VCF ;

Sette, PS ;

da Silva, JV ;

de Araujo, VC ;

Gomez, RS .

JOURNAL OF ENDODONTICS, 1998, 24 (01) :36-37

[7]

CD57+ T-LYMPHOCYTES ARE DERIVED FROM CD57- PRECURSORS BY DIFFERENTIATION OCCURRING IN LATE IMMUNE-RESPONSES [J].

DANGEAC, AD ;

MONIER, S ;

PILLING, D ;

TRAVAGLIOENCINOZA, A ;

REME, T ;

SALMON, M .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (07) :1503-1511

[8]

Frassanito MA, 1998, BRIT J HAEMATOL, V100, P469

[9]

Germinal centre CD4+ T cells are an important site of HIV replication in vivo [J].

Hufert, FT ;

vanLunzen, J ;

Janossy, G ;

Bertram, S ;

Schmitz, J ;

Haller, O ;

Racz, P ;

vonLaer, D .

AIDS, 1997, 11 (07) :849-857

[10]

CELLS INFILTRATING HUMAN PERIAPICAL INFLAMMATORY LESIONS [J].

KONTIAINEN, S ;

RANTA, H ;

LAUTENSCHLAGER, I .

JOURNAL OF ORAL PATHOLOGY & MEDICINE, 1986, 15 (10) :544-546

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