Preparation of carborane-containing polymers by atom transfer radical polymerization

被引：19

作者：

Gratton, Stephanie E. A.

Parrott, Matthew C.

Adronov, Alex

机构：

[1] McMaster Univ, Dept Chem, Hamilton, ON L8S 4M1, Canada

[2] McMaster Univ, Brockhouse Inst Mat Res, Hamilton, ON L8S 4M1, Canada

来源：

JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS | 2005年 / 15卷 / 04期

基金：

加拿大创新基金会;

关键词：

atom-transfer radical polymerization; block copolymers; boron neutron capture therapy; carboranes; neutron irradiation;

D O I：

10.1007/s10904-006-9000-8

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A para-carborane functionalized acrylate monomer was prepared and utilized in atom transfer radical polymerizations to produce carborane-loaded linear polymers. Copolymerization with a poly(ethylene glycol) monomethyl ether methacrylate (MPEGMA) allowed for the preparation of a water-soluble random copolymer having a boron content of 7.4%. In addition, a homopolymer of the carborane acrylate monomer was utilized as a macroinitiator to produce a block copolymer where the second block consisted of MPEGMA units. Each of the resulting polymer structures was irradiated with thermal neutrons to observe boron neutron capture events occurring within the boron-loaded polymers. The characteristic gamma radiation that signifies neutron capture events was observed at similar to 480 keV.

引用

页码：469 / 475

页数：7

共 19 条

[1] DICESIUM N-SUCCINIMIDYL 3-(UNDECAHYDRO-CLOSO-DODECABORANYLDITHIO)PROPIONATE, A NOVEL HETEROBIFUNCTIONAL BORONATING AGENT [J].